Freely Filtered 050: CLASSIC Trial

The Filtrate look at the latest contribution to Fluid Wars, this one looking at late resuscitation.

NephJC CLASSIC summary

The Filtrate:

Joel Topf

Swapnil Hiremath

Jennie Lin

Special Guests:

Priya Yenebere @PriRenalAKI Transplant nephrologist at Indiana University School of Medicine. She is a current NSMC Intern.

J Pedro Teixeira @NephCrit_NM ICU Nephrologist at the University of New Mexico.

Editor:

Priya Yenebere


Show Notes:

Critical Care Nephrology Critical Care Nephrology: Core Curriculum 2020 by Benjamin R Griffin, Kathleen D Liu, and J Pedro Teixeira.

Critical Care Rheumatology Dual-Trained Rheumatologists Take Multidisciplinary Approach to Their Patients

Med-Peds to Nephrology

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock by Emanuel Rivers

ProMISe: Trial of Early, Goal-Directed Resuscitation for Septic Shock

ARISE: Goal-Directed Resuscitation for Patients with Early Septic Shock

ProCESS: A Randomized Trial of Protocol-Based Care for Early Septic ShockThe Filtrate:

Rinaldo Bellomo and micro circulatory disorders as cause of AKI in sepsis. Septic acute kidney injury: new concepts

Comparison of Two Fluid-Management Strategies in Acute Lung Injury (FACTT) The negative trial we accept as a positive trial because of the secondary outcomes.

The prime minister of Finland was caught on the dance floor. This is a bad thing? (NY Times)

Deferred Consent: A New Approach for Resuscitation Research on Comatose Patients

Lactate conversion MediCalc

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mottling score is a strong predictor of 14-day mortality in septic patients whatever vasopressor doses and other tissue perfusion parameters

Critical Care Reviews Podcast: CLASSIC Trial Results Presentation

What is the most George Constanza-esque reason you broke up with someone? (reddit)

Bonferroni correction

The Importance of Fluid Management in Acute Lung Injury Secondary to Septic Shock

Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery in the NEJM. RELIEF, NephJC discussion

Effect of an Early Resuscitation Protocol on In-hospital Mortality Among Adults With Sepsis and Hypotension: A Randomized Clinical Trial in JAMA

FEAST Trial: Mortality after Fluid Bolus in African Children with Severe Infection

Rings of Power on Amazon Prime

Why the Hobbit trilogy sucked

Industry on HBO

Sandman 2022 on Netflix

Where did Liverpool FC go wrong with the 2021/2022 Premier League? (Quora)

CRRT Academy at University of Alabama with

2020 Robert G. Narins Award Recipient: Ashita Tolwani, MD, MS (YouTube)

Life as a Nephrologist podcast on CritCare Nephrology

Continuous KRT: A Contemporary Review by J. Pedro Teixeira, Javier A. Neyra and Ashita Tolwani

University of New Mexico Nephrology Program. Apply to their fellowship.

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