This week on NephTrials we will discuss the PROTECT-V trial, a platform trial for preventing COVID-19 infections in the vulnerable kidney populations.
BEATing Calciphylaxis with an Adaptive Platform design
Breaking the discord between patients’ goals and traditional trial outcomes: the SWIFT trial
Master Drugs Meet The Master Protocol: The Renal Lifecycle Trial
Efficiency in clinical trials: Getting to the H4RT of registry design
Run-in periods in clinical trials: What can we ACHIEVE?
Creativity in Counting with Cluster RCTs
Pragmatic trials in nephrology: Bridging the gap between efficacy and effectiveness?
NNT: Number Needed to Treat or No Need to Think?
In this edition of #Nephstats, we look at Number Needed to Treat (NNT), a controversial topic creates ripples and roars on social media amongst stat savvy physicians, epidemiologists and biostatisticians. This seems like such a simple and easy number to make sense of a trial’s importance - what could be controversial or wrong about it?