Freely filtered looks at the landmark study of finerenone in heart failure with preserved ejection fraction, The FINE ARTS study
The Filtrate
Joel Topf
Swapnil Hiremath
AC Gomez
Jordy Cohen
Nayan Arora
Special Guest
Brendon Nuen
Editing by
Simon Topf and Nayan Arora
Show Notes
FINEARTS-HF in NEJM
FINEARTS Kidney outcomes in JACC
FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes in Nature Medicine discussion in NephJC
BARACH-D: Low-dose spironolactone and cardiovascular outcomes in moderate stage chronic kidney disease: a randomized controlled trial (Nature Medicine)
Live Freely Filtered at KidneyWk
Swapnil comes out as a SpiroStan post to NephJC
TOPCAT
TOPCAT primary publication
TOPCAT North American results
TOPCAT funny business explained
AHA/ACC/HFSA Heart Failure Guidelines (PDF)
SGLT2i are 2a
MRA are a 2b
ARBs are a 2b
ARNI are a 2b
Kansas city cardiomyopathy questionnaire in patients with CKD without a diagnosis of heart failure: https://pubmed.ncbi.nlm.nih.gov/21187260/
GFR slope with steroidal MRAs in HF: https://onlinelibrary.wiley.com/doi/10.1002/ejhf.2635
Why Has it Been Challenging to Modify Kidney Disease Progression in Patients With Heart Failure? (JACC)
Tubular Secretions
Swap: Disclaimer on Apple TV
AC: Duo Lingo Plushy (Amazon)
Nayan: The Puzzle Box
Jordy: Project Hail Mary
Brendon has a podcast, The Kidney Compass with Shikha Wadhwani. And he recommends singer-songwriter, Maggie Rogers (YouTube)
Joel: The Singularity Is Nearer: When We Merge with AI by Ray Kurzweil
Closing music, Tim Yau with The Kidney Connection