Episode 74: Amino Acids for AKI

Amino acids, an effective treatment for AKI?

 

The Filtrate:

Jennie Lin

Joel Topf

Josh Waitzman

Swapnil Hiremath

With Special Guests

Pedro Teixeira

Jay Koyner

Editor

Sophia Ambruso

Show Notes

The article: A Randomized Trial of Intravenous Amino Acids for Kidney Protection

NephJC Summary

KDIGO Clinical Practice Guideline for Acute Kidney Injury (Website)

Steve Coca study Evaluation of Short-Term Changes in Serum Creatinine Level as a Meaningful End Point in Randomized Clinical Trials (PubMed)

Using Nephrocheck to prevent AKI: Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial (PubMed)

Brenner’s Review of protein intake and renal hemodynamics: Dietary Protein Intake and the Progressive Nature of Kidney Disease: — The Role of Hemodynamically Mediated Glomerular Injury in the Pathogenesis of Progressive Glomerular Sclerosis in Aging, Renal Ablation, and Intrinsic Renal Disease (NEJM)

Husain-Syed a look at preoperative renal functional reserve and risk of AKI: Preoperative Renal Functional Reserve Predicts Risk of Acute Kidney Injury After Cardiac Operation (PubMed)

Dana Fuhrman review of renal functional reserve: The Role of Renal Functional Reserve in Predicting Acute Kidney Injury (PubMed)

Use of SGLT2i prevented AKI in the placebo controlled trials. Clinical Adverse Events Associated with Sodium-Glucose Cotransporter 2 Inhibitors: A Meta-Analysis Involving 10 Randomized Clinical Trials and 71 553 Individuals (PubMed)

Assessment of P values for demographic data in randomized controlled trials (PubMed)

Tubular Secretions

Swapnil The Lord of the Rings: Rings of Power Season 2 on Amazon Prime (Wikipedia)

Josh Fortnite (Website)

Pedro CRRT Academy at University of Alabama Birmingham (Website)

Jay Koyner Slow Horses on AppleTV (Wikipedia)

Jennie Linn #KidneyWk Run Club Friday 10/25 at 6:15 am PST Meet in front of Sally’s Fish House ~2 miles. Easy pace (10-12 min/mile) (Strava)

Joel Topf Your Honor on Netflix (Wikipedia)