Another dogma shredding trial about diuretics, this time hydrochlorothiazide ability to reduce symptomatic kidney stone events and kidney stone growth goes on trial.
The Filtrate:
Joel Topf
Swapnil Hiremath
Josh Waitzman
Nayan Arora
Sophia Ambruso
With Special Guest:
Megan Prochaska Assistant professor of medicine at University of Chicago
John Asplin Medical Director Consultant LithoLink (Twitter)
Editor:
Joel Topf
Show Notes:
The LithoLink website
Stone Camp tweet
Prevention of Repeated Episodes of Kidney Stones in Adults: A Clinical Practice Guideline From the American College of Physicians (link)
NOSTONE in the NEJM and NephJC
Fred Coe Google Scholar | YouTube | Blog
Hypercalcuria. Curhan et al. 24-h uric acid excretion and the risk of kidney stones PubMed
EQUIL2 software to evaluate urinary super saturation
Anna Zisman Racial Differences in Risk Factors for Kidney Stone Formation (CJASN)
Potassium Citrate on GoodRx
Potassium and citrate by Fred Coe (blog)
Thiazide Diuretics and Fracture Risk: A Systematic Review and Meta‐Analysis of Randomized Clinical Trials (PubMed)
Chlorthalidone promotes mineral retention in patients with idiopathic hypercalciuria by Coe et al (PubMed)
NHANES 24-hour urine Na (Abstract)
Kidney Stone risk is reduced with empagliflozin (PubMed)
Prospective trial to determine the effect of SGLT2i on urinary supersaturation (BMJ Open)
GLP agonists and kidney stone risk
Tubular Secretions
Swap: Star Wars: Thrawn Series by Timothy Zahn (Penguin Random House)
Josh: Little League
Megan: Renal related podcasts
Sophia Renal Stone Camp and ABCKidney.com
Nayan: Ted Lasso Robert Galbraithand The Comoran Strike Novels (home page)
John: Fred Coe’s Blog
Joel: Spiderman across the Spider-Verse (Wikipedia)