The Filtrate (minus Swapnil) gather to talk about the treatment of hypernatremia.

Show Notes:

Joel Topf

Jennie Lin

Matt Sparks

Samira Farouk

The strange story of Jennifer Strange.

https://insiderexclusive.com/radios-deadly-stunts-the-jennifer-strange-story/

Water Poker

https://www.thelocal.se/20120706/41878

Nintendo Game Consoles

https://en.wikipedia.org/wiki/Nintendo_video_game_consoles

2019 Narins winner, Mitchel Rosner on MDMA induced hyponatremia

https://www.ncbi.nlm.nih.gov/pubmed/18684895

And Rosner again on exercise induced hyponatremia.

https://cjasn.asnjournals.org/content/2/1/151

The Arieff article on the dangers of severe hyponatremia: Hyponatremia, Convulsions, Respiratory Arrest, and Permanent Brain Damage after Elective Surgery in Healthy Women

https://www.nejm.org/doi/full/10.1056/NEJM198606123142401

The Richard Sterns article on the dangers of rapid correction of hyponatremia: Osmotic Demyelination Syndrome Following Correction of Hyponatremia

https://www.nejm.org/doi/10.1056/NEJM198606123142402

The editorial by the man himself, Robert Narins: Therapy of Hyponatremia

https://www.nejm.org/doi/full/10.1056/NEJM198606123142409

The infant study showing seizures associated with rapid correction of hypernatremia.

https://www.ncbi.nlm.nih.gov/pubmed/35558?dopt=Abstract

Follow up study with oral rehydration.

https://www.ncbi.nlm.nih.gov/pubmed/3958850?dopt=Abstract

The Linder study of adults admitted to the ICU

https://www.ncbi.nlm.nih.gov/pubmed/18037096

French study on patients presenting to the ER with hypernatremia.

https://bmcnephrol.biomedcentral.com/articles/10.1186/1471-2369-15-37

Study on US veterans showing poorer outcomes with slow correction of hypernatremia.

https://www.ncbi.nlm.nih.gov/pubmed/21358313

Cerebral edema during the treatment of DKA.

https://emj.bmj.com/content/21/2/141

The MIMIC 3 Database. MIMIC is an openly available dataset developed by the MIT Lab for Computational Physiology, comprising deidentified health data associated with ~40,000 critical care patients. It includes demographics, vital signs, laboratory tests, medications, and more.

https://mimic.physionet.org

Chalrson Comorbidity Index

https://www.mdcalc.com/charlson-comorbidity-index-cci#creator-insights

The paper: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.

https://www.ncbi.nlm.nih.gov/pubmed/3558716

JCI article on organic brain osmnoles in response to hypernatremia

https://www.ncbi.nlm.nih.gov/pubmed/2332498?dopt=Abstract

John Booth on the value of MIMIC 3

https://twitter.com/ThePeanutKidney/status/1128742219471642624

Sri Lekha on checking labs in hypernatremia

https://twitter.com/LTummalapalli/status/1128479041634226176

Steve Coca on chunky water administration

https://twitter.com/scoca1/status/1128744643422769152

Steve Coca musing the Cersei’s sodium level

https://twitter.com/scoca1/status/1128698514026975232

Steve Coca swearing in High Valarlian:

https://twitter.com/scoca1/status/1128629713826721792

Steve Coca proving the non-existence of hypernatremia therapy being associated with brain damage through the inability of trial lawyers to find and sue doctors for this issue:

https://twitter.com/scoca1/status/1128652586612080642

The original paper on the Kardashian Index

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-014-0424-0

Kardashian Index Calculator

http://theinformationalturn.net/kardashian-index/

Facebook CEO Mark Zuckerberg says the ‘future is private’

https://www.theverge.com/2019/4/30/18524188/facebook-f8-keynote-mark-zuckerberg-privacy-future-2019

Khenar Jhaveri et al on ‘WhatsApp’ening in nephrology training

https://academic.oup.com/ckj/advance-article/doi/10.1093/ckj/sfz045/5482109

Mike Morrison’s video on how to rebuild the scientific poster

https://www.youtube.com/watch?v=1RwJbhkCA58

Mike’s Twitter: https://twitter.com/mikemorrison?lang=en with lot’s of examples of his design in the wild.