Matt Sparks and The Renal Fellow Network has been polling the community about the top nephrology stories of the year since 2010. Matt joins Swap and Joel to discuss the top stories of 2021.
The Filtrate:
Joel Topf
Swapnil Hiremath
Matt Sparks
Editor:
Joel Topf
Show Notes:
The 2010 RFN Top Nephrology Stories
The 2021 NephJC Top Nephrology Stories
Number 10: AKIKI
Number 9: Effect of Salt Substitution on Cardiovascular Events and Death
The Salt Substitute and Stroke Study (SSaSS) in the NEJM
The Salt Substitute and Stroke Study (SSaSS) in NephJC
FDA Issues Final Guidance Regarding Use of an Alternate Name for Potassium Chloride in Food Labeling
Number 8: AURORA, voclosporin for Lupus Nephritis
Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1) in the Lancet
Number 7: FIGARO trial of finerenone for CV outcomes
Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes in the NEJM
Rates of Hyperkalemia after Publication of the Randomized Aldactone Evaluation Study by David Juurlink
Joel’s intermission
FDA Rejections
Number 6: Pig Kidney Transplant.
As covered in the New York Times
Clinical Pig Kidney Xenotransplantation: How Close Are We? from JASN
Number 5: KDIGO Blood Pressure Guidelines
And on Freely Filtered
Matt’s article on ACCORD he wrote for RFN as a fellow
Number 4: Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease (CLICK)
Number 3: Dapagliflozin helps IgA nephropathy
FDA OKs First Proteinuria Drug for IgA Nephropathy: delayed released budesonide
Number 2: New eGFR formulas, now race free.
New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race in the NEJM
Number 16: Fixing ADPKD in mice
Renal plasticity revealed through reversal of polycystic kidney disease in mice in Nature Genetics
Press release from Yale
Number 1: KDIGO GN Guidelines
Last Month in Nephrology skeptical of all the Rituximab