Freely Filter goes where we have never gone before…a Phase 2 trial!
The Filtrate:
Joel Topf
Jennie Lin
Josh Waitzman
With Special Guest:
AC Gomez MedPeds nephrology fellow at Mass General/Brigham and Boston Children’s | Twitter
Gentian Hall Assistant Professor of Medicine Duke Department of Medicine
Editor:
Sophia Ambruso
Show Notes:
APOL1 review by the OG Scientists APOL1 Nephropathy: From Genetics to Clinical Applications
MYH9 and APOL1 connection: The population genetics of chronic kidney disease: insights from the MYH9–APOL1 locus
Worldwide Frequencies of APOL1 Renal Risk Variants (NEJM)
Kidney Disease-Associated APOL1 Variants Have Dose-Dependent, Dominant Toxic Gain-of-Function
End-Stage Renal Disease in African Americans With Lupus Nephritis Is Associated With APOL1
HEK293 Cells Wikipedia
Tubular Secretions
Josh: From Serial and the New York Times: The Retrievals
Jennie: Marathon induced hyponatremia (NEJM)
Donate to the NKF of Illinoise in honor of Jennie’s really long run
Donate to New England Donor Services in honor of Josh’s much shorter ruin
Gentian: Vivien Thomas wikipedia. HBO Movie: Something the Lord Made
AC: Talking to the FDA about SGLT2i Tweet
Joel: NephJC 2023 Fund drive