Wash U Episode 14: Immune complex GN

  • Lupus nephritis
  • Poststreptococcal GN
  • Membranous nephropathy
  • IgA nephropathy
  • MPGN

Other than giving headaches to medical students, what do all of these disorders have in common?  They all fall under the umbrella of "immune complex mediated" glomerulonephritis.  Of course, there are others as well - immunotactoid, fibrillary, C3 glomerulopathy, the list goes on and on.  But sometimes a biopsy and a case don't fall into the simple bucket that we expect, and oftentimes clinicians are left feeling a bit unsure of themselves because the lines between these diseases blur together.  The February video from the Wash U Nephrology Web Series left us scratching our heads a bit, but real life cases aren't always quite like the textbook.  Check it out.

Welcome back! February renal path series is here and presents a bit of an unusual case. Sometimes the histology doesn't show exactly what you expect to see, and you have to think outside of the box! Hope you enjoy the discussion of the case and the biopsy interpretation.