Blog — NephJC

March 23, 2025

Background

Brian Rifkin

KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD. These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.

March 11, 2025

Background

Cristina Adriana Popa

REGENCY: A B-Cell Super Destroyer in Lupus

This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨

February 24, 2025

Background

Cristina Adriana Popa

Hunting Primary Hyperaldosteronism: are MRAs a ...

This week, we will continue with February’s aldosterone leitmotif: do mineralocorticoid receptor antagonists (MRAs) truly blind the diagnostic in unilateral hypraldosteronism? Is this the article the mythbuster? Draw your own conclusions

February 10, 2025

Background

Brian Rifkin

Undercover Aldosterone

This week, we will discuss the origins of primary hyperaldosteronism in normotensive patients. Could this undetected anomaly be the cause of idiopathic hypertension and CKD?

January 21, 2025

Background

swapnil hiremath

HOPE-ing and Coping with Pain in Dialysis

This week, we will discuss the HOPE trial - no not that one - the one in dialysis that was a LBCT in 2024. Should we look beyond analgesics to non-pharmacological options more seriously?

Future Topic

joel topf

February 5, 2024

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🤔 Flozination reduces kidney stones

joel topf

February 5, 2024

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Sodium-Glucose Cotransporter 2 Inhibitors and Nephrolithiasis Risk in Patients With Type 2 Diabetes (JAMA 2024)

joel topf

February 5, 2024

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🤔 Maternal kidney mass associates with gestational and fetal outcomes

joel topf

February 5, 2024

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Any reduction in maternal kidney mass makes a difference during pregnancy in gestational and fetal outcome. (Kidney International 2024)

joel topf

February 5, 2024

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🤔 Adjusting Tolvaptan based on Urine osmolality in ADPKD

joel topf

February 5, 2024

Future Topic

Prospective Study on Individualized Dose Adjustment of Tolvaptan Based on Urinary Osmolality in Patients With ADPKD (KI Reports Jan 2024)