Episode 038 Voclosporin is a new calcineurin inhibitors with reliable pharmacokinetics, i.e. no more therapeutic drug monitoring, and it was able to improve complete renal remission in lupus nephritis. But all that glitters is not gold. Join us as we dig deep into the landmark AURORA1 trial.
Freely Filtered 037: The first Guideline Draft: KDIGO Hypertension Guidelines
Freely Filtered 036: AKIKI-2, How soon is now?
Episode 036 AKIKI-2. Nephrology has been the beneficiary of a handful of studies examining the impact of the timing of the initiation of dialysis in AKI. One of these trials, AKIKI, now has a genuine sequel. In 2016 AKIKI was the first multi-center RCT examining early initiation of dialysis versus late initiation of dialysis and showed that early initiation not only failed to improve patient outcomes but resulted in a significant number of patients receiving dialysis that would have recovered kidney function without intervention had they only been randomized to the late arm. Now five years later we are reviewing the sequel which asks the next logical question, “If delayed dialysis is as good as early dialysis is even later dialysis equivalent or even better?”
Freely Filtered 035: ASN Fellow Survey, COVID-19 Edition
Episode 035: The COVID-19 Pandemic changed everything and last fall the ASN set out to document how it affected our nephrology fellows. The ASN Workforce Committee adapted the Annual Fellow Survey to assess how the pandemic affected nephrology fellows in terms of burn out, education, and enthusiasm for the specialty.
Freely Filtered 034: Terlipressin for Hepatorenal Syndrome
Freely Filtered 033: The Roxadustat Statistics shenanigans
Freely Filtered 032: Animal House
Freely Filtered 031: Roxadustat
Freely Filtered 030: DAPA-CKD
Freely Filtered 029: Belimumab for lupus nephritis
Freely Filtered 028: Finerenone for diabetic kidney disease
Freely Filtered 027: Long and deep on the KDIGO Diabetes Guidelines
Freely Filtered 026: Interventional Nephrology meet NephJC, NephJC meet Interventional Nephrology
Freely Filtered 025: Making sense of albuminuria, proteinuria, and the dipstick
Episode 025: The filtrate welcome Drs. Morgan Grams and Talar Kharadjian to discuss the recent paper in Annals of Internal Medicine: Conversion of Urine Protein-Creatinine Ratio or Urine Dipstick Protein to Urine Albumin-Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis: An Individual Participant-Based Meta-analysis