joel topf

September 19, 2022

Background

ADVOR TRIAL - Can the addition of a little buddy make a big difference ?

joel topf

September 19, 2022

Background

ADVOR TRIAL - Can the addition of a little buddy make a big difference ?

This week, we will discuss The ADVOR trial, possibly the only randomized, placebo controlled trial of sequential nephron blockade ever. Could the use of acetazolamide in acute decompensated heart failure make a difference?

swapnil hiremath

September 6, 2022

Background

Vancomycin and Piperacillin-Tazobactam: Friends or foes?

swapnil hiremath

September 6, 2022

Background

Vancomycin and Piperacillin-Tazobactam: Friends or foes?

Pip/Tazo and Vanco is the new new kid on the block for antibiotic induced AKI. Does it deserve its bad boy reputation?

joel topf

August 22, 2022

Background

The NephJC Summer Book Club: 'Codebreaker'

joel topf

August 22, 2022

Background

The NephJC Summer Book Club: 'Codebreaker'

It’s back! The NephJC Summer Book Club with Walter Isaacson’s book which is part Jennifer Doudna biography and part an examination of CRISPER technology and its implications.

swapnil hiremath

August 9, 2022

Background

Is Less Always More? The Case of Fluids in Septic Shock

swapnil hiremath

August 9, 2022

Background

Is Less Always More? The Case of Fluids in Septic Shock

This week, we will discuss the CLASSIC trial, pitting a restrictive versus a standard fluid resuscitation strategy in septic shock.

swapnil hiremath

July 26, 2022

Background

Sodium HF: Control-Salt-Delete

swapnil hiremath

July 26, 2022

Background

July is Heart Month! After arrhythmias we turn to heart failure and sodium restriction with the SODIUM-HF trial from the Lancet

swapnil hiremath

July 11, 2022

Background

Arrhythmias with Antibiotics

swapnil hiremath

July 11, 2022

Background

This week, we will discuss the potential harm of widespread antibiotic use, and how some of them may contribute to sudden death in hemodialysis

swapnil hiremath

June 21, 2022

Background

Should we buy what Donor-Derived Cell-Free DNA is Selling?

swapnil hiremath

June 21, 2022

Background

Should we buy what Donor-Derived Cell-Free DNA is Selling?

This week, we will discuss the ADMIRAL DNA, which sells the cell-free donor derived DNA as the shiny new thing which will make diagnostics easy in kidney transplants. Or will it?

Jamie Willows

June 5, 2022

Background

Re-TESTING Steroids for IgA Nephropathy

Jamie Willows

June 5, 2022

Background

Coming up next we have the TESTING RCT (again), with updated results on methylprednisolone treatment for IgA nephropathy.

Jade Teakell

May 23, 2022

Background

A New CHAPter in an Old Story

Jade Teakell

May 23, 2022

Background

This week, we have a practice changing study about the treatment of mild hypertension during pregnancy. Join us on Tuesday (9 EDT) and Wednesday (9 IST).

Guest User

May 10, 2022

Background

CHIPping away at Kidney Disease

Guest User

May 10, 2022

Background

This week, we will discuss the study on the effect of clonal hematopoiesis on the kidneys. What is CHIP anyways?

Jade Teakell

April 19, 2022

Background

ISPD Peritonitis Update 2022

Jade Teakell

April 19, 2022

Background

We have a long awaited huge update on the ISPD peritonitis guidelines. Bugs change and we need to change how we treat them. We break down the evidence for you in this summary

Jamie Willows

April 4, 2022

Background

Induction for ANCA-Associated Vasculitis: It’s ComPLEX

Jamie Willows

April 4, 2022

Background

Induction for ANCA-Associated Vasculitis: It’s ComPLEX

This week we discuss an updated systematic review and meta-analysis on the effects of plasma exchange in patients with ANCA-associated vasculitis

Jade Teakell

March 21, 2022

Background

Diuretic Resistance in Heart Failure

Jade Teakell

March 21, 2022

Background

This week we discuss the mechanistic study looking at diuretic resistance. Timed with the NephMadness cardiorenal region!

swapnil hiremath

March 6, 2022

Background

Pain, Paracetamol and Pressure

swapnil hiremath

March 6, 2022

Background

This week, we will discuss the PATH BP trial, which demolishes the supposed benign nature of acetaminophen/paracetamol.

swapnil hiremath

February 22, 2022

Background

Xenotransplantation: The Future is Here-ish

swapnil hiremath

February 22, 2022

Background

Xenotransplantation: The Future is Here-ish

This week, we will discuss the published case report from the UAB on one of the early xenotransplantations from genetically engineered pig kidneys.

swapnil hiremath

February 8, 2022

Background

Revisiting the Ideal Time: The Case of Chronic Dialysis

swapnil hiremath

February 8, 2022

Background

Revisiting the Ideal Time: The Case of Chronic Dialysis

This week, we will discuss the intricate analysis using target trial emulation - applied for the initiation of dialysis in CKD. Let’s fix problems of lead time and immortal time bias.

swapnil hiremath

January 25, 2022

Background

Scheduling Steroids to Remedy Relapses

swapnil hiremath

January 25, 2022

Background

This week, we will discuss two trials with a joint IPNA JC session. PREDNOS 2 explores and explodes the steroids use in URTI to prevent relapse practice, while another noninferiority trial reports use of lower dose steroids in managing relapses.

Guest User

January 10, 2022

Background

Nephrin in Nephrotic Syndrome

Guest User

January 10, 2022

Background

This week, we will discuss the discovery of anti-nephrin antibodies and the elucidation of their role in minimal change disease

swapnil hiremath

December 21, 2021

Background

LUST but do not fall in Love with POCUS yet?

swapnil hiremath

December 21, 2021

Background

LUST but do not fall in Love with POCUS yet?

This week, we will discuss the LUST trial, to see if use of a POCUS changes your focus enough to help improve clinical outcomes

swapnil hiremath

December 7, 2021

Background

Old is Gold: CLICK for Chlorthalidone

swapnil hiremath

December 7, 2021

Background

This week, we will discuss the CLICK trial. Another medical reversal - showing that this old and cheap drug, chlorthalidone, might actually work in advanced CKD. Click through to read more.