This week, we will discuss the phase 3 ORIGIN3 trial of atacicept, an APRIL/BAFF inhibitor for use in IgAN.
ORIGIN-3: The Visual Abstract
ORIGIN-3: El Resumen Visual
ORIGIN-3 ha llegado a NephJC con atacicept en NIgA.
Un paso sólido hacia una terapia dirigida anti BAFF/APRIL, que aborda la fisiopatología desde su origen. ¡Las señales tempranas son prometedoras!
Revisa el resumen visual realizado por Clemens Weber
Kidney transplant diaries: achieving immune tolerance by chimerism
A thread on the most relevant part of the chat on tolerance induction in HLA-matched transplant with donor hematopoietic stem cells (MDR-101). Thread by Akshaya Jayachandran.
Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression?
ASIs Advance: NephJC Shorts on BaxHTN
NephJC Shorts: ALCHEMIST trial and Meta-analysis
In ESRD is spironolactone an overACHIEVEr?
The ACHIEVE visual abstract
Does spironolactone decrease cardiovascular disease and heart failure hospitalizations in patients on dialysis?
Check out this crisp VA by Dr Akshaya Jayachandran.
NephJC Shorts: The end of the Fluid Wars?
A dose of CONFIDENCE: Building evidence for finerenone-empagliflozin synergy in diabetic kidney disease
CONFIDENCE Visual Abstract
Check out the beautiful visual abstract made by NephJC intern Michelle Fravel.
NephJC Shorts: BedMed and Chronotherapy
Do nudges increase the use of GDMT in diabetic CKD?
Is tacrolimus superior to MMF in pediatric steroid sensitive nephrotic syndrome?
Ensayo STAMP: ¿Tacrolimus o Micofenolato en el síndrome nefrótico pediátrico?
El síndrome nefrótico en niños puede implicar recaídas frecuentes, alta carga de esteroides y decisiones terapéuticas difíciles. Entonces, ¿cuál mantiene mejor la remisión: tacrolimus o micofenolato de mofetilo?
Revisa el VA y únete a la discusión en #NephJC
The STAMP Trial VA: Who Gets the Approval—TAC or MMF in Pediatric Nephrotic Syndrome?
Nephrotic syndrome in kids can mean frequent relapses, high steroid burden, and tough treatment choices. So which helps maintain remission better: Tacrolimus or MMF?
See the Visual Abstract Krithika Mohan
TAC or MMF—what works better in pediatric nephrotic syndrome?
Nephrotic syndrome in children, especially those with frequent relapses or steroid dependence, remains a therapeutic challenge. The STAMP trial compared tacrolimus and mycophenolate mofetil to help guide treatment decisions.
STAMP of Approval: Tacrolimus vs MMF in Pediatric Nephrotic Syndrome
Does desmopressin help with post kidney biopsy bleeding?
Check out this thread, summarizing discussions on two studies.