Background
Jade Teakell
FLOZINATing to the Future- Long Term Effects of ...

This week, we will discuss post-trial follow-up for EMPA-Kidney. What are the longer-term effects of empagliflozin for patients with chronic kidney disease?

FLOZINATing to the Future- Long Term Effects of Empagliflozin in Patients with CKD
Background
Brian Rifkin
The Ondansetron Ballet: Torsades de Pointes

Nausea is a very common and distressing problem. Some medications that treat nausea carry a higher risk for arrhythmias, like Torsades de Pointes, and sudden cardiac death. Is ondansetron safe for use in patients on hemodialysis?

The Ondansetron Ballet: Torsades de Pointes
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Cristina Adriana Popa
Re”FINE”ing the role of non steroidal MRAs in ...

This week, we will discuss non-steroidal mineralocorticoid antagonist in the multiverse of cardiovascular-kidney-metabolic. What FINEHEART pooled analysis would add to what we already learned from FIDELIO-DKD trial?

Re”FINE”ing the role of non steroidal MRAs in Cardio Kidney Metabolic syndrome
Background
Cristina Adriana Popa
Playing It Safe: Can Felzartamab Fill the Gap ...

This week is time antibody mediated rejection treatment in kidney transplant. A new molecule targeting CD38, on the horizon, safely tested in a phase 2 trial

Playing It Safe: Can Felzartamab Fill the Gap in AMR Treatment?
Background
Jade Teakell
The pressure is on! Unravelling the ESPRIT of ...

This week, we will discuss the ongoing saga of blood pressure targets in patients with hypertension. This time its ESPRIT (Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing Risk of Vascular Events) making a case for case for intensive BP control in most hypertensive individuals, including those with a history of diabetes and stroke.

The pressure is on! Unravelling the ESPRIT of Intensive vs Standard BP Control

tweetorial

Here We KDIGO Again: Lupus Nephritis 2024

New KDIGO guidelines since 2021, Lupus Nephritis is seeing lots of new therapeutics in the pipeline.

Salt in the wounds?

Fascinating observational study on hyponatraemia correction rates this week, catch-up here.

Natriuresis (UNa) measurements to guide diuretic strategies?

TenTweetNephJC on X. Natriuresis guidance for intensification of diuretics is one strategy to PUSH decongestion in patient’s with acute heart failure.

Precision medicine in AIN?

TenTweetNephJC on AIN = TenXNephJC on AIN = XXNephJC on AIN…? Twitter not being called twitter is confusing.

Fluid Wars: Plasmalyte Strikes Back

Patients are given a lot of fluid post-transplant, but which to choose? Catch up on the latest evidence here.

TenXeetNephJC? TenPostNephJC? It's HDF and CONVINCE anyway.

Huge trial on our core work, catch-up here

#TenTweetsNephJC does STS and CUA

WIth no RCTs to go on, we review a meta-analysis on sodium thiosulphate for calciphylaxis

Giving oral bicarb raises serum bicarb

RCT of PO sodium bicarbonate in patients with renal transplant to see if impacts stability of renal function - catch up here!

RITAZAREM - how to manage relapse in AAV

Was anyone really backing azathioprine against vitamin R in relapsed ANCA-associated vasculitis? Catch-up on the RCT here.

Be excited, no need to APOLogize

Huge news in APOL1 nephropathy - ten tweets to fill you in here:

Gathering no moss

Thiazides to prevent rolling stones - the Ten Tweet summary of NOSTONE is here.

More options for immunosuppression in IgA....

Check out the tweetorial for the MAIN event - does MMF work in IgA Nephropathy?

TenTweet summary - cardiac testing prior to kidney transplant

It’s a controversial topic: click below to catch-up

Confusing AF

Now that twitter has recovered from its downtime, a catch-up tweetorial on apixaban for AF in patients on dialysis for you.

Water, Water Everywhere: The Diuretic Wars Continue!

What’s your loop and thiazide of choice? Do you know which diuretics are better, faster, stronger? This week’s TenTweets is a two-fer (Chlorthalidone vs HCTZ and Furosemide vs Torsemide). Tweetorial catch-up here.

IgA and steroids: the saga continues

Drug reps pitching you Nefecon? Catch-up with the RCT in our #TenTweetNephJC tweetorial

Checking in on MyTEMP - #TenTweetNephJC

The last NephJC of the year brought us a cool discussion on if cooling dialysate could help mitigate the effects of intradialytic hypotension. Get caught up with the chat in the latest edition of #TenTweetNephJC.

New player in resistant hypertension?

This week we discussed aprocitentan, another endothelin receptor antagonist, this time being explored in the resistant hypertension arena - you know the #TenTweetNephJC drill, if you want a rapid catch up then here’s your place!

Don't Stop Me Now!

If you missed the latest NephJC discussion, at least read the highlights here.

You gotta know when to hold’em and know when to fold’em. Review the #TenTweetNephJC for the STOP ACEi Trial, and always hold onto your ACEi.