This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD. These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.
This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨
This week, we will continue with February’s aldosterone leitmotif: do mineralocorticoid receptor antagonists (MRAs) truly blind the diagnostic in unilateral hypraldosteronism? Is this the article the mythbuster? Draw your own conclusions
This week, we will discuss the origins of primary hyperaldosteronism in normotensive patients. Could this undetected anomaly be the cause of idiopathic hypertension and CKD?
This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD. These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.
El hiperaldosteronismo primario (HAP) no es solo una entidad de hipertensión resistente; este estudio revela un continuo fisiopatológico que inicia en personas normotensas.
A través de pruebas dinámicas, ¿podría el HAP ser la base oculta de una proporción significativa de la hipertensión? ¿Cómo cambia nuestro enfoque en el diagnóstico y tratamiento?
👀 Veamos el resumen visual creado por Brian Rifkin 🎨✨ y 💬 únete a la conversación en #NephJC por Bluesky.
Should we call 2024 the Renaissance of nephrology? It was probably the richest year in RCTs in the nephrology world, reflected in the higher number of Late-Breaking Clinical Trials sessions at every big nephrology congress. Probably 1st place won’t surprise anyone; it was the anticipated FLOW of the year, but this Top 10 Nephrology Stories definitely includes some unexpected titles
El Resumen Visual
¿Realmente existen diferencias entre los pacientes con enfermedades renales raras de otras causas de ERC?
Veamos este resumen visual creado por el miembro de la facultad NephEdC, Brian Rifkin, el cual activa el RaDaR hacia las enfermedades renales raras.
Are patients with rare kidney diseases different from other CKD? Check out the beautiful VAs by NSMC faculty Brian Rifkin and Cristina Popa
New KDIGO guidelines since 2021, Lupus Nephritis is seeing lots of new therapeutics in the pipeline.
Welcome to #TenTweetNephJC
— Nephrology Journal Club (@NephJC) February 9, 2024
✳️10 tweets #NephJC catch-up ✳️
✴️Let’s recap the 2024 KDIGO Lupus Nephritis Guidelines!@BradRovin @AyuobIsabelle @meg21212 @cellotonelli @Gordon7Craig#KDIGO2024
❣️Didn’t get to join the 🐺pack for this one, no worries we’ll help you wolf it down 🥩! pic.twitter.com/Xg8NdWdH23
2023 brought us has dogma shredding data on hyponatremia and the importance of different diuretics. It has new therapies for old diseases like IgA and hypertension. New drugs for new diseases like inaxaplin for AMKD. And it has new data on old debates like what IVF is best and do thiazides really prevent kidney stones. It is a great list. Dig in!
Yet another new medication class for use in the RAAS cascade. BI 690517, an aldosterone synthase inhibitor, has been shown to significantly reduce proteinuria with or without empagliflozin. VA by Brian Rifkin.
TenTweetNephJC on X. Natriuresis guidance for intensification of diuretics is one strategy to PUSH decongestion in patient’s with acute heart failure.
Welcome to #TenTweetNephJC
— Nephrology Journal Club (@NephJC) October 5, 2023
Adequate decongestion to prevent rehospitalization & excess mortality are the goals when treating HF. So, why do we fail so often?
This week we look at natriuresis guided diuretic therapy in hospitalized HF patients.
✳️10 tweets #NephJC catch-up ✳️ pic.twitter.com/PjDKcscTOV
If you missed the latest NephJC discussion, at least read the highlights here.
You gotta know when to hold’em and know when to fold’em. Review the #TenTweetNephJC for the STOP ACEi Trial, and always hold onto your ACEi.
Welcome to #TenTweetNephJC
— Nephrology Journal Club (@NephJC) December 1, 2022
✳️ 10 tweets #NephJC catch-up ✳️ pic.twitter.com/n8dcopDLPT
